MDCAT Chemistry

Phenols Acidity MDCAT Quiz with Answers

Phenols Acidity MDCAT Quiz is quite vital in organic chemistry, and especially for MDCAT students, since the acid-base property predominantly influences the reactivity and behavior of the phenolic compound. Phenols are more acidic than alcohols because of the property of the phenoxide ion, C₆H₅O⁻, which can be stabilized through the aromatic ring. In light of this fact, they behave differently when reacting with bases, which determines them to be helpful during most synthetic procedures.

Acidity of Phenols: Phenols are weak acids, and their acidity is a consequence of the ability of the hydroxyl group (-OH) to lose a proton (H⁺), forming the phenoxide ion (C₆H₅O⁻). This ion is stabilized by resonance with the aromatic ring, which delocalizes the negative charge over the ring, making it easier for phenols to release a proton compared to alcohols. The phenoxide ion formed is more stable than the alkoxide ion (R-O⁻) formed from alcohols, and this contributes to the higher acidity of phenols.

Substituent effect: Substituents present on the benzene ring may affect the acidity of phenols. Electron-withdrawing groups (−NO₂, −CN, −COOH) increase the acidity of phenols by stabilizing the negative charge on the oxygen atom of the phenoxide ion. On the other hand, electron-donating groups (−OH, −OCH₃) decrease the acidity of phenols as they reduce the ring’s ability to stabilize the negative charge through resonance. So, phenols with electron-withdrawing groups at the ortho and para position to the hydroxyl group are more acidic.

Comparison of Phenols with Alcohols: Phenols are generally more acidic than alcohols due to the resonance stabilization of the phenoxide ion. In alcohols, the negative charge formed after proton loss is localized on the oxygen atom, which is less stable. This is why phenols can react with bases such as sodium hydroxide (NaOH) to form phenoxide salts, while alcohols require much stronger bases for deprotonation.

Quiz: Test Your Knowledge of Phenols Acidity

Our MDCAT Quiz on phenols acidity will help you test your knowledge in the factors that influence the acidity of phenols. The quiz contains questions related to resonance stabilization, the effect of different substituents, and the comparison between phenols and alcohols regarding acidity. Practicing these questions will ensure you’re ready for acidity-related queries in the MDCAT exam.

0

Get Your Username and Password for MDCAT Tests
Sign Up Now

Free Flashcard: Key Insights on Phenols Acidity

Our Free Flashcard set on phenols acidity provides a clear-cut summary of the factors that influence phenol acidity, including the role of resonance and the effect of substituents. These flashcards are a great tool for reinforcing your understanding and preparing for the MDCAT exam.

Phenols are more acidic than alcohols due to the presence of __________.

The acidity of phenols increases with the presence of __________ groups.

The phenol group (-OH) in phenol is attached to a __________ carbon.

The negative charge on the phenoxide ion after deprotonation is stabilized by __________.

The pKa of phenol is __________.

The presence of an electron-withdrawing group on the aromatic ring __________ the acidity of phenols.

The phenoxide ion is stabilized through __________.

Phenols are more acidic than alcohols because the negative charge on the oxygen atom in the phenoxide ion is __________.

The addition of an electron-donating group such as -OH to the phenol ring __________ the acidity.

The pKa of phenol is __________ than alcohols due to its ability to stabilize the conjugate base.

The phenoxide ion can stabilize the negative charge by __________.

The acidity of phenol is decreased by __________ substituents on the ring.

The electron-withdrawing group that most increases the acidity of phenols is __________.

Phenol reacts with sodium to form __________.

The phenoxide ion can be stabilized by __________ groups.

The acidity of phenol increases when the substituent is in the __________ position.

Phenol has a lower pKa than ethanol because of __________.

The acidity of phenol decreases with the addition of __________ substituents.

The resonance structures of the phenoxide ion contribute to its __________.

Phenols are less acidic than carboxylic acids because __________.

The presence of a __________ group on the phenol ring increases acidity.

In phenols, the phenoxide ion has a __________ charge.

The conjugate base of phenol is called __________.

The stronger the electron-withdrawing group, the __________ the acidity of phenols.

The acidity of phenols is __________ in the presence of a hydroxyl group at the ortho or para position.

The acidity of phenols is __________ by the presence of a halogen atom.

The acidity of phenol is __________ when the substituent is a methyl group.

The acidity of phenols is __________ by the presence of an alkyl group.

The acidic strength of phenol can be compared to that of __________.

The ability of phenol to act as a Brønsted-Lowry acid is due to its ability to __________.

Experience the real exam environment with our expertly designed collection of over 25,000 MCQs MDCAT Mock Tests.

View Your Dashboard

Related Articles

Leave a Reply

Your email address will not be published. Required fields are marked *

Back to top button