MDCAT Biology

Glycolysis Glycolytic Pathway Aerobic Respiration MDCAT Quiz with Answers

Glycolysis is the first step of cellular respiration, where one molecule of glucose-a six-carbon sugar-is split into two molecules of pyruvate-a three-carbon compound. It takes place in cytoplasm and is a feature common to both aerobic and anaerobic respiration. In the context of respiration involving oxygen, it acts as the preparatory phase where it generates intermediates and energy carriers that are necessary for later steps like the Krebs cycle and the Electron Transport Chain (ETC). Glycolysis is the process of ten sequentially occurring enzyme-catalyzed reactions which may be divided into two: the energy investment phase where ATP is spent, and the energy payoff phase where ATP and NADH are produced. In every molecule of glucose, glycolysis produces 2 ATP, 2 NADH, and 2 pyruvate molecules. A good understanding of glycolysis helps MDCAT students master the hierarchy of metabolic pathways and their role in energy production.

MDCAT Quiz
An MDCAT Quiz on Glycolysis and the Glycolytic Pathway will test your understanding of the important steps, enzymes, and energy outputs of this process. This quiz will be based on some topics like substrate-level phosphorylation, the role of enzymes like hexokinase and phosphofructokinase, and the fate of pyruvate in aerobic respiration. These quizzes ensure that you prepare well for MDCAT related questions.

Free Flashcards for Quick Revision
Free Flashcards on Glycolysis will provide you with concise summaries of the key steps in the pathway, including glucose phosphorylation, cleavage, and ATP production. The flashcards will also show the energy yield of glycolysis and NADH as an electron carrier. They are a perfect tool for revising the key components of the glycolytic pathway, ensuring you’re ready for the MDCAT exam.

Mastering Glycolysis and the Glycolytic Pathway in Aerobic Respiration is essential to understanding how glucose is broken down to produce energy in living organisms. Use our quizzes and flashcards to strengthen your knowledge and better prepare for exams!

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What is the first step of glycolysis?

Glucose phosphorylation

Which enzyme converts glucose to glucose-6-phosphate in glycolysis?

Hexokinase

What is the end product of glycolysis?

Pyruvate

How many ATP molecules are consumed in the energy-investment phase of glycolysis?

2

What is produced during the energy payoff phase of glycolysis?

ATP and NADH

How many molecules of ATP are produced per glucose molecule during glycolysis?

2

What molecule is used to form ATP in glycolysis?

Glucose-6-phosphate

Which molecule is reduced in glycolysis to form NADH?

NAD+

What happens to pyruvate at the end of glycolysis in the presence of oxygen?

It enters the Krebs cycle

Which process follows glycolysis when oxygen is present?

Aerobic respiration

How many molecules of NADH are produced during glycolysis?

2

What molecule is produced in glycolysis that enters the mitochondria for further processing?

Pyruvate

What enzyme catalyzes the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate in glycolysis?

Phosphofructokinase

How many molecules of ATP are net produced by glycolysis from one molecule of glucose?

2

What is the fate of NADH produced in glycolysis when oxygen is present?

It is used in the electron transport chain

In which cellular compartment does glycolysis take place?

Cytoplasm

Which molecule is the direct precursor to acetyl-CoA in aerobic respiration?

Pyruvate

What is the role of NAD+ in glycolysis?

It accepts electrons

What is the second phase of glycolysis called?

Energy investment phase

What is the main purpose of the glycolytic pathway?

To break down glucose to generate ATP

Which of the following occurs in the presence of oxygen following glycolysis?

Pyruvate enters the Krebs cycle

What is the total ATP gain per glucose molecule after glycolysis and the Krebs cycle?

38 ATP

What type of phosphorylation occurs during glycolysis?

Substrate-level phosphorylation

Which molecule enters the electron transport chain after being generated in glycolysis?

NADH

Which compound accumulates in anaerobic conditions due to the lack of oxygen?

Lactic acid

What is the enzyme that converts phosphoenolpyruvate to pyruvate in glycolysis?

Pyruvate kinase

What is the role of ATP in glycolysis?

It activates glucose

How is the pyruvate from glycolysis processed in anaerobic conditions in animals?

Converted to lactic acid

What is the fate of pyruvate in aerobic respiration after glycolysis?

Converted to acetyl-CoA

What is the role of hexokinase in the glycolytic pathway?

Phosphorylates glucose

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