Everyday Science

DNA, RNA & Genetic Code MCQs With Answer

Which of the following is the sugar present in RNA?
A) Deoxyribose
B) Ribose
C) Glucose
D) Fructose

Answer
B) Ribose

In DNA, adenine (A) always pairs with which nitrogenous base?
A) Cytosine
B) Thymine
C) Guanine
D) Uracil

Answer
B) Thymine

The central dogma of molecular biology describes the flow of genetic information as:
A) Protein → RNA → DNA
B) DNA → RNA → Protein
C) RNA → DNA → Protein
D) DNA → Protein → RNA

Answer
B) DNA → RNA → Protein

Which enzyme is responsible for DNA replication?
A) RNA polymerase
B) DNA polymerase
C) Ligase
D) Helicase

Answer
B) DNA polymerase

RNA differs from DNA because it:
A) Contains uracil instead of thymine
B) Is single-stranded
C) Has ribose sugar instead of deoxyribose
D) All of the above

Answer
D) All of the above

Which of the following nitrogenous bases is found in RNA but not in DNA?
A) Cytosine
B) Thymine
C) Uracil
D) Guanine

Answer
C) Uracil

The process of copying DNA into RNA is called:
A) Translation
B) Replication
C) Transcription
D) Mutation

Answer
C) Transcription

The three-letter sequence in mRNA that codes for an amino acid is called:
A) Anticodon
B) Nucleotide
C) Codon
D) Gene

Answer
C) Codon

What is the function of tRNA during translation?
A) Carries genetic information
B) Forms ribosomes
C) Brings amino acids to the ribosome
D) Catalyzes peptide bond formation

Answer
C) Brings amino acids to the ribosome

Which molecule carries the genetic code from the nucleus to the ribosome?
A) tRNA
B) mRNA
C) rRNA
D) DNA

Answer
B) mRNA

Which enzyme unwinds the DNA double helix during replication?
A) Helicase
B) Ligase
C) Primase
D) RNA polymerase

Answer
A) Helicase

What type of bond holds the two strands of DNA together?
A) Covalent bond
B) Hydrogen bond
C) Ionic bond
D) Peptide bond

Answer
B) Hydrogen bond

Which of the following is a stop codon?
A) AUG
B) UAA
C) GGG
D) AAA

Answer
B) UAA

Which RNA type forms the structural component of ribosomes?
A) mRNA
B) rRNA
C) tRNA
D) snRNA

Answer
B) rRNA

The start codon in most organisms is:
A) UGA
B) AUG
C) UAA
D) UAG

Answer
B) AUG

What is the complementary DNA strand for the sequence 5′-ATGCGA-3′?
A) 5′-TACGCT-3′
B) 5′-CGTATC-3′
C) 5′-GCTAGT-3′
D) 5′-TAGCGT-3′

Answer
A) 5′-TACGCT-3′

Which process converts mRNA into a polypeptide?
A) Replication
B) Transcription
C) Translation
D) Mutation

Answer
C) Translation

Which of the following best describes a gene?
A) A segment of RNA that codes for a protein
B) A segment of DNA that codes for a protein
C) A protein molecule in the nucleus
D) A sequence of amino acids

Answer
B) A segment of DNA that codes for a protein

Which nitrogenous base pairs with cytosine in DNA?
A) Adenine
B) Thymine
C) Guanine
D) Uracil

Answer
C) Guanine

Which scientist(s) discovered the double-helix structure of DNA?
A) Watson and Crick
B) Franklin and Wilkins
C) Hershey and Chase
D) Griffith and Avery

Answer
A) Watson and Crick

What is the role of ribosomes in protein synthesis?
A) Replicating DNA
B) Synthesizing mRNA
C) Translating mRNA into proteins
D) Transporting amino acids

Answer
C) Translating mRNA into proteins

Which enzyme is responsible for transcribing RNA from DNA?
A) DNA polymerase
B) RNA polymerase
C) Ligase
D) Helicase

Answer
B) RNA polymerase

A mutation that changes one nucleotide without changing the amino acid sequence is called:
A) Missense mutation
B) Nonsense mutation
C) Silent mutation
D) Frameshift mutation

Answer
C) Silent mutation

What is the function of a promoter in transcription?
A) Signals where transcription should begin
B) Binds amino acids together
C) Removes introns from mRNA
D) Attaches ribosomes to tRNA

Answer
A) Signals where transcription should begin

Which of the following mutations is most likely to be harmful?
A) Silent mutation
B) Frameshift mutation
C) Missense mutation
D) Point mutation

Answer
B) Frameshift mutation

Which molecule brings amino acids to the ribosome during translation?
A) tRNA
B) mRNA
C) rRNA
D) DNA

Answer
A) tRNA

What is the term for non-coding regions of mRNA that are removed before translation?
A) Exons
B) Codons
C) Anticodons
D) Introns

Answer
D) Introns

Which process repairs mistakes in DNA replication?
A) Translation
B) DNA proofreading
C) Splicing
D) Codon recognition

Answer
B) DNA proofreading

Which of the following best describes the genetic code?
A) Overlapping and ambiguous
B) Universal and redundant
C) Species-specific
D) Contains only 10 codons

Answer
B) Universal and redundant

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